Motif ID: TFAP2{A,C}.p2

Z-value: 1.912


Transcription factors associated with TFAP2{A,C}.p2:

Gene SymbolEntrez IDGene Name
TFAP2A 7020 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2C 7022 transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TFAP2Ahg19_v1_chr6_-_10419786_10419796-0.371.0e-03Click!
TFAP2Chg19_v1_chr20_+_55204307_55204554-0.361.3e-03Click!


Activity profile for motif TFAP2{A,C}.p2.

activity profile for motif TFAP2{A,C}.p2


Sorted Z-values histogram for motif TFAP2{A,C}.p2

Sorted Z-values for motif TFAP2{A,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP2{A,C}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_151561653 14.350 AKAP12
A kinase (PRKA) anchor protein 12
chr19_+_7580987 12.765 NM_018083
ZNF358
zinc finger protein 358
chr6_+_151561508 11.590 AKAP12
A kinase (PRKA) anchor protein 12
chr6_+_151561571 10.716


chr4_-_57976516 10.399 IGFBP7
insulin-like growth factor binding protein 7
chr17_+_54671059 10.066 NM_005450
NOG
noggin
chr3_-_45267068 9.564 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr3_-_45267620 9.262 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr16_+_226678 8.968 NM_000558
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr20_+_33146500 8.763 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr16_+_222845 8.273 NM_000517
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr10_-_43762366 8.103 NM_145313
RASGEF1A
RasGEF domain family, member 1A
chr14_+_105992930 8.097 NM_025268
TMEM121
transmembrane protein 121
chr4_-_57976355 8.085 IGFBP7
insulin-like growth factor binding protein 7
chr3_+_71803200 7.858 NM_018971
GPR27
G protein-coupled receptor 27
chr20_+_36531548 7.615 VSTM2L
V-set and transmembrane domain containing 2 like
chr16_+_22825806 7.265 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr5_+_92920592 7.198 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr20_-_62130390 6.835 NM_001958
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr20_+_36531498 6.756 NM_080607
VSTM2L
V-set and transmembrane domain containing 2 like
chr11_+_69924407 6.666 NM_018043
ANO1
anoctamin 1, calcium activated chloride channel
chr11_-_128392061 6.617 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr7_-_106301329 6.613 NM_175884
C7orf74
chromosome 7 open reading frame 74
chr5_-_168727715 6.556 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr15_+_81293286 6.492 NM_022566
MESDC1
mesoderm development candidate 1
chr11_+_12132063 6.444 NM_014632
MICAL2
microtubule associated monoxygenase, calponin and LIM domain containing 2
chr11_+_117070039 6.421 NM_001001522
NM_003186
TAGLN

transgelin

chr11_-_119187811 6.339 NM_006500
MCAM
melanoma cell adhesion molecule
chr1_-_85358851 6.266 NM_012152
LPAR3
lysophosphatidic acid receptor 3
chr5_+_129240453 6.246 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr12_+_569542 6.186 NM_173593
B4GALNT3
beta-1,4-N-acetyl-galactosaminyl transferase 3
chr1_+_90098693 6.176 LRRC8C
leucine rich repeat containing 8 family, member C
chr17_+_43299277 6.168 NM_005892
FMNL1
formin-like 1
chr11_-_128391888 6.154 ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr2_+_113403433 6.126 NM_005415
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr20_-_62284701 6.120 NM_015894
STMN3
stathmin-like 3
chr1_-_228135587 5.989 NM_003395
WNT9A
wingless-type MMTV integration site family, member 9A
chr16_+_67686813 5.952 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr21_-_28217272 5.925 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr1_-_95007139 5.912 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr16_+_19179534 5.882 NM_016524
SYT17
synaptotagmin XVII
chrX_-_48693934 5.869 NM_013271
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chrX_-_153095810 5.868 PDZD4
PDZ domain containing 4
chr8_-_29207795 5.851 NM_001394
DUSP4
dual specificity phosphatase 4
chr9_+_99212379 5.769 NM_014282
HABP4
hyaluronan binding protein 4
chr16_-_325867 5.755 NM_003834
NM_183337
RGS11

regulator of G-protein signaling 11

chr9_+_126773851 5.677 NM_004789
LHX2
LIM homeobox 2
chr13_-_20806533 5.630 NM_001110219
NM_001110220
NM_001110221
GJB6


gap junction protein, beta 6, 30kDa


chr3_-_127541160 5.627 NM_007283
MGLL
monoglyceride lipase
chr15_+_101420032 5.626 ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr17_+_74380676 5.624 NM_001142601
NM_021972
NM_182965
SPHK1


sphingosine kinase 1


chr15_-_74726258 5.585 NM_001146029
NM_003612
SEMA7A

semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)

chrX_-_38079980 5.569 NM_001170750
NM_001170751
NM_001170752
NM_006307
SRPX



sushi-repeat containing protein, X-linked



chr12_+_66218879 5.538 HMGA2
high mobility group AT-hook 2
chr19_+_35521591 5.512 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr22_+_19711065 5.467 NM_000407
GP1BB
glycoprotein Ib (platelet), beta polypeptide
chr21_-_28217692 5.441 NM_006988
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr5_+_71403040 5.405 NM_005909
MAP1B
microtubule-associated protein 1B
chr12_-_6665220 5.372 NM_001039670
NM_001193457
NM_080730
IFFO1


intermediate filament family orphan 1


chr2_-_224903933 5.362 NM_001136528
NM_006216
SERPINE2

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

chr3_-_127541975 5.351 NM_001003794
MGLL
monoglyceride lipase
chr15_+_101420004 5.346 NM_000693
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr17_+_1959512 5.346 NM_001098202
HIC1
hypermethylated in cancer 1
chr4_-_57976550 5.314 NM_001253835
NM_001553
IGFBP7

insulin-like growth factor binding protein 7

chr4_-_177713664 5.295 NM_005429
VEGFC
vascular endothelial growth factor C
chr11_+_128564130 5.293 FLI1
Friend leukemia virus integration 1
chr19_+_15218141 5.192 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr1_+_90098624 5.174 LRRC8C
leucine rich repeat containing 8 family, member C
chr1_-_21059132 5.141 NM_001103160
NM_001103161
SH2D5

SH2 domain containing 5

chr1_-_41328002 5.120 NM_133467
CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr11_-_61684981 5.065 NM_013401
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr7_-_45960738 5.062 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr14_-_101034261 5.039 NM_001159531
BEGAIN
brain-enriched guanylate kinase-associated homolog (rat)
chr21_-_32931289 5.032 NM_003253
TIAM1
T-cell lymphoma invasion and metastasis 1
chr4_+_2061238 4.999 NM_178557
NAT8L
N-acetyltransferase 8-like (GCN5-related, putative)
chr1_+_90098643 4.977 NM_032270
LRRC8C
leucine rich repeat containing 8 family, member C
chr14_-_61190458 4.974 NM_017420
SIX4
SIX homeobox 4
chr10_-_44144266 4.963 NM_006973
ZNF32
zinc finger protein 32
chr19_+_16187306 4.956 TPM4
tropomyosin 4
chr19_+_16187047 4.876 NM_003290
TPM4
tropomyosin 4
chr20_+_55966440 4.870 NM_017495
NM_183425
RBM38

RNA binding motif protein 38

chr5_-_159739482 4.856 NM_024565
CCNJL
cyclin J-like
chrX_-_153095996 4.844 NM_032512
PDZD4
PDZ domain containing 4
chr22_-_39639967 4.836 PDGFB
platelet-derived growth factor beta polypeptide
chr19_+_34972866 4.799 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr6_+_144471631 4.797 NM_003764
STX11
syntaxin 11
chr19_+_16187266 4.786 TPM4
tropomyosin 4
chr3_-_128206704 4.769 NM_001145662
GATA2
GATA binding protein 2
chr12_-_93965521 4.750 LOC144481
uncharacterized LOC144481
chr3_+_111718006 4.748 NM_001008273
TAGLN3
transgelin 3
chr2_-_235405692 4.696 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr2_-_45236521 4.695 NM_016932
SIX2
SIX homeobox 2
chr4_+_4861371 4.687 NM_002448
MSX1
msh homeobox 1
chr4_-_85419386 4.670 NM_006168
NKX6-1
NK6 homeobox 1
chr17_-_73874634 4.624 NM_033452
TRIM47
tripartite motif containing 47
chr1_-_41328019 4.550 CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr1_+_178063237 4.528 RASAL2
RAS protein activator like 2
chr8_-_13133956 4.527


chr1_+_178063302 4.527 RASAL2
RAS protein activator like 2
chr10_-_77161136 4.525 ZNF503
zinc finger protein 503
chr4_+_3465032 4.513 NM_001164673
NM_173660
DOK7

docking protein 7

chr5_-_149681935 4.494 ARSI
arylsulfatase family, member I
chr14_+_70346113 4.451 NM_001034852
NM_022137
SMOC1

SPARC related modular calcium binding 1

chrX_-_153095746 4.448 PDZD4
PDZ domain containing 4
chr17_-_73874056 4.428 TRIM47
tripartite motif containing 47
chr12_+_66218141 4.423 NM_003483
NM_003484
HMGA2

high mobility group AT-hook 2

chr19_+_589849 4.395 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr22_+_31487315 4.378 SMTN
smoothelin
chr19_-_1863425 4.370 KLF16
Kruppel-like factor 16
chr2_-_1748285 4.370 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr2_+_37571752 4.369 NM_012413
QPCT
glutaminyl-peptide cyclotransferase
chr2_-_224903324 4.356 NM_001136530
SERPINE2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr1_-_20812271 4.353 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr21_+_47531369 4.349 COL6A2
collagen, type VI, alpha 2
chr11_+_46402333 4.337 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr2_-_233792825 4.330 NM_001114090
NGEF
neuronal guanine nucleotide exchange factor
chr17_-_41623652 4.322 NM_001079675
ETV4
ets variant 4
chr2_-_86564632 4.288 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr12_+_104850641 4.258 NM_001173982
NM_018413
CHST11

carbohydrate (chondroitin 4) sulfotransferase 11

chr6_+_41606193 4.256 NM_005586
MDFI
MyoD family inhibitor
chr20_-_25038501 4.252 NM_001252675
NM_001252677
NM_032501
ACSS1


acyl-CoA synthetase short-chain family member 1


chr2_-_20212448 4.240 NM_002381
MATN3
matrilin 3
chr7_+_128470462 4.237 NM_001127487
NM_001458
FLNC

filamin C, gamma

chr2_+_103236147 4.211 NM_003048
SLC9A2
solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr11_+_128563993 4.209 FLI1
Friend leukemia virus integration 1
chr12_+_104850762 4.198 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr18_+_9708322 4.191 RAB31
RAB31, member RAS oncogene family
chr13_-_41768533 4.181 NM_032138
KBTBD7
kelch repeat and BTB (POZ) domain containing 7
chr5_+_133450353 4.178 NM_003202
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr19_+_16187315 4.163 TPM4
tropomyosin 4
chr2_-_1748213 4.118 PXDN
peroxidasin homolog (Drosophila)
chr5_+_34656482 4.106 RAI14
retinoic acid induced 14
chr2_-_20212408 4.104 MATN3
matrilin 3
chr17_+_1958354 4.093 NM_006497
HIC1
hypermethylated in cancer 1
chr2_-_1748317 4.075 PXDN
peroxidasin homolog (Drosophila)
chr9_+_131183122 4.074 CERCAM
cerebral endothelial cell adhesion molecule
chr10_-_77161539 4.058 ZNF503
zinc finger protein 503
chr8_-_133492751 4.025 KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr2_-_218843541 4.011 TNS1
tensin 1
chr12_+_104850784 4.004 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr8_-_133493003 4.000 NM_004519
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr12_+_104850750 3.997 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr10_-_99094264 3.960 FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chrX_+_68725077 3.959 NM_015686
FAM155B
family with sequence similarity 155, member B
chr12_+_58005217 3.947 NM_182947
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr22_-_20792107 3.943 NM_153334
NM_182895
SCARF2

scavenger receptor class F, member 2

chr12_+_53491448 3.937 IGFBP6
insulin-like growth factor binding protein 6
chr12_+_111471827 3.936 NM_015267
CUX2
cut-like homeobox 2
chr19_+_39989603 3.919 DLL3
delta-like 3 (Drosophila)
chr19_-_1863546 3.918 NM_031918
KLF16
Kruppel-like factor 16
chr10_+_17271859 3.917 VIM
vimentin
chr22_+_51113069 3.916 NM_001080420
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr16_+_89989686 3.916 NM_006086
TUBB3
tubulin, beta 3 class III
chr15_+_41786055 3.909 NM_002220
ITPKA
inositol-trisphosphate 3-kinase A
chr2_+_231577624 3.900 CAB39
calcium binding protein 39
chr3_-_197282805 3.888 NM_004051
NM_203314
BDH1

3-hydroxybutyrate dehydrogenase, type 1

chr17_-_46703613 3.885 NM_024017
HOXB9
homeobox B9
chr12_+_104850986 3.879 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr22_+_31489343 3.875 SMTN
smoothelin
chr1_+_23037329 3.859 NM_004442
NM_017449
EPHB2

EPH receptor B2

chr3_+_111717585 3.847 NM_001008272
NM_013259
TAGLN3

transgelin 3

chr8_+_22436641 3.838 PDLIM2
PDZ and LIM domain 2 (mystique)
chr8_-_38325524 3.824 FGFR1
fibroblast growth factor receptor 1
chr5_+_34656367 3.824 NM_001145522
NM_015577
RAI14

retinoic acid induced 14

chr17_+_74864427 3.816 NM_001199172
NM_144677
MGAT5B

mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B

chr10_+_17271956 3.808 VIM
vimentin
chr11_-_2950593 3.795 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr2_+_231577536 3.790 NM_016289
CAB39
calcium binding protein 39
chr10_-_77161424 3.787 NM_032772
ZNF503
zinc finger protein 503
chr2_-_43453724 3.782 ZFP36L2
zinc finger protein 36, C3H type-like 2
chr17_+_64960754 3.779 NM_014405
CACNG4
calcium channel, voltage-dependent, gamma subunit 4
chr5_+_140346289 3.765 NM_031883
PCDHAC2
protocadherin alpha subfamily C, 2
chr1_+_92495484 3.758 NM_173567
EPHX4
epoxide hydrolase 4
chr4_+_1005395 3.752 FGFRL1
fibroblast growth factor receptor-like 1
chr15_-_65067696 3.748 NM_194272
RBPMS2
RNA binding protein with multiple splicing 2
chr12_-_71003622 3.744 NM_001206971
NM_001206972
NM_002837
PTPRB


protein tyrosine phosphatase, receptor type, B


chr9_-_86153048 3.743 NM_001244959
NM_174938
FRMD3

FERM domain containing 3

chr6_+_151561094 3.710 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr21_+_47518012 3.705 NM_001849
NM_058174
NM_058175
COL6A2


collagen, type VI, alpha 2


chr19_+_35168558 3.693 NM_001012320
NM_018443
ZNF302

zinc finger protein 302

chr19_-_41859830 3.648 NM_000660
TGFB1
transforming growth factor, beta 1
chr5_-_121413967 3.640 LOX
lysyl oxidase
chr8_+_145582267 3.629 NM_024531
GPR172A
G protein-coupled receptor 172A
chr9_+_131644427 3.609 LRRC8A
leucine rich repeat containing 8 family, member A
chr22_+_31031672 3.596 NM_001001479
SLC35E4
solute carrier family 35, member E4
chr9_+_131644368 3.587 NM_001127245
NM_019594
LRRC8A

leucine rich repeat containing 8 family, member A

chr10_+_64133915 3.578 NM_014951
NM_199450
NM_199451
ZNF365


zinc finger protein 365


chr16_+_57126439 3.564 NM_152727
CPNE2
copine II
chr15_+_73976537 3.558


chr2_-_43453146 3.548 ZFP36L2
zinc finger protein 36, C3H type-like 2
chr3_-_128207366 3.544 NM_001145661
GATA2
GATA binding protein 2
chr21_+_38071990 3.536 NM_005069
NM_009586
SIM2

single-minded homolog 2 (Drosophila)

chr8_+_56792392 3.528 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr10_+_104404195 3.524 NM_030912
TRIM8
tripartite motif containing 8
chr2_+_239756672 3.523 NM_057179
TWIST2
twist homolog 2 (Drosophila)
chr16_+_57126494 3.511 CPNE2
copine II
chr2_+_173292344 3.507 ITGA6
integrin, alpha 6
chr1_+_178062955 3.500 RASAL2
RAS protein activator like 2
chr11_+_94277005 3.497 NM_002033
PIWIL4
FUT4
piwi-like 4 (Drosophila)
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chrX_-_153151537 3.495



Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.91 9.83e-16 GO:0009653 anatomical structure morphogenesis
1.85 1.98e-13 GO:0007399 nervous system development
1.80 2.71e-13 GO:0023051 regulation of signaling
1.86 6.17e-13 GO:0009966 regulation of signal transduction
1.66 7.01e-12 GO:0030154 cell differentiation
1.64 1.16e-11 GO:0048869 cellular developmental process
2.48 1.48e-11 GO:0000904 cell morphogenesis involved in differentiation
1.53 1.65e-11 GO:0048731 system development
2.26 6.86e-11 GO:0032989 cellular component morphogenesis
1.43 7.00e-11 GO:0032502 developmental process
1.45 1.06e-10 GO:0007275 multicellular organismal development
2.29 1.34e-10 GO:0000902 cell morphogenesis
1.99 2.54e-10 GO:0048468 cell development
1.47 5.70e-10 GO:0048856 anatomical structure development
1.97 7.25e-10 GO:0022008 neurogenesis
2.01 7.46e-10 GO:0048699 generation of neurons
1.26 9.91e-10 GO:0050794 regulation of cellular process
1.62 4.36e-09 GO:0048583 regulation of response to stimulus
1.93 8.18e-09 GO:0050793 regulation of developmental process
1.39 1.10e-08 GO:0023052 signaling
2.27 3.16e-08 GO:0031175 neuron projection development
1.23 4.83e-08 GO:0050789 regulation of biological process
1.21 6.02e-08 GO:0065007 biological regulation
2.37 6.24e-08 GO:0007409 axonogenesis
1.40 8.54e-08 GO:0007165 signal transduction
1.98 9.44e-08 GO:2000026 regulation of multicellular organismal development
2.31 9.87e-08 GO:0048812 neuron projection morphogenesis
1.72 1.04e-07 GO:0051239 regulation of multicellular organismal process
2.32 1.19e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
2.05 2.40e-07 GO:0030030 cell projection organization
1.51 5.73e-07 GO:0048523 negative regulation of cellular process
1.75 1.00e-06 GO:0010646 regulation of cell communication
2.07 1.16e-06 GO:0048666 neuron development
2.14 1.25e-06 GO:0048858 cell projection morphogenesis
2.13 1.86e-06 GO:0032990 cell part morphogenesis
1.94 1.92e-06 GO:0030182 neuron differentiation
1.95 2.70e-06 GO:0045595 regulation of cell differentiation
1.45 5.66e-06 GO:0048519 negative regulation of biological process
2.16 8.42e-06 GO:0023057 negative regulation of signaling
2.36 8.53e-06 GO:0007411 axon guidance
2.16 9.33e-06 GO:0010648 negative regulation of cell communication
1.98 1.13e-05 GO:0042060 wound healing
1.81 1.34e-05 GO:0051128 regulation of cellular component organization
2.13 1.54e-05 GO:0051094 positive regulation of developmental process
2.19 1.68e-05 GO:0009968 negative regulation of signal transduction
1.78 1.90e-05 GO:0040011 locomotion
1.97 2.51e-05 GO:0050878 regulation of body fluid levels
2.05 2.85e-05 GO:0007599 hemostasis
3.04 3.15e-05 GO:0034330 cell junction organization
3.93 4.48e-05 GO:0002576 platelet degranulation
2.13 4.64e-05 GO:0040008 regulation of growth
2.03 5.04e-05 GO:0007596 blood coagulation
2.03 5.04e-05 GO:0050817 coagulation
1.25 6.83e-05 GO:0032501 multicellular organismal process
2.47 8.21e-05 GO:0030036 actin cytoskeleton organization
2.30 9.71e-05 GO:0022603 regulation of anatomical structure morphogenesis
2.28 1.01e-04 GO:0060284 regulation of cell development
2.33 1.25e-04 GO:0030029 actin filament-based process
1.43 1.57e-04 GO:0065008 regulation of biological quality
1.95 2.41e-04 GO:0006935 chemotaxis
1.95 2.41e-04 GO:0042330 taxis
1.39 2.52e-04 GO:0048522 positive regulation of cellular process
2.23 2.95e-04 GO:0001501 skeletal system development
1.36 3.08e-04 GO:0048518 positive regulation of biological process
2.44 3.76e-04 GO:0030168 platelet activation
1.94 4.31e-04 GO:0048585 negative regulation of response to stimulus
2.95 4.91e-04 GO:0034329 cell junction assembly
1.64 5.69e-04 GO:0009605 response to external stimulus
2.24 7.88e-04 GO:0051270 regulation of cellular component movement
1.30 9.05e-04 GO:0016043 cellular component organization
1.26 1.20e-03 GO:0051716 cellular response to stimulus
2.38 1.43e-03 GO:0002009 morphogenesis of an epithelium
2.33 1.72e-03 GO:0001558 regulation of cell growth
1.43 2.62e-03 GO:0007166 cell surface receptor linked signaling pathway
1.63 2.63e-03 GO:0009611 response to wounding
1.73 2.68e-03 GO:0009890 negative regulation of biosynthetic process
1.28 2.86e-03 GO:0071840 cellular component organization or biogenesis
2.17 4.53e-03 GO:0051960 regulation of nervous system development
2.21 4.87e-03 GO:0030334 regulation of cell migration
2.04 6.46e-03 GO:0045597 positive regulation of cell differentiation
2.19 6.69e-03 GO:2000145 regulation of cell motility
1.73 7.11e-03 GO:0001932 regulation of protein phosphorylation
1.76 7.26e-03 GO:0009887 organ morphogenesis
2.21 8.87e-03 GO:0050767 regulation of neurogenesis
2.10 1.11e-02 GO:0040012 regulation of locomotion
2.07 1.21e-02 GO:0048729 tissue morphogenesis
2.92 1.23e-02 GO:0010720 positive regulation of cell development
2.58 1.27e-02 GO:0001655 urogenital system development
2.13 1.66e-02 GO:0045596 negative regulation of cell differentiation
2.01 1.67e-02 GO:0051093 negative regulation of developmental process
1.31 1.75e-02 GO:0071842 cellular component organization at cellular level
1.69 1.82e-02 GO:0007167 enzyme linked receptor protein signaling pathway
2.58 1.95e-02 GO:0050678 regulation of epithelial cell proliferation
1.68 2.19e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.09 2.19e-02 GO:0009987 cellular process
1.77 2.67e-02 GO:0007417 central nervous system development
1.43 2.69e-02 GO:0065009 regulation of molecular function
1.66 2.82e-02 GO:0031327 negative regulation of cellular biosynthetic process
2.78 2.82e-02 GO:0072001 renal system development
2.64 2.98e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.65 3.08e-02 GO:0019220 regulation of phosphate metabolic process
1.65 3.08e-02 GO:0051174 regulation of phosphorus metabolic process
3.25 3.25e-02 GO:0048638 regulation of developmental growth
2.61 3.45e-02 GO:0022604 regulation of cell morphogenesis
1.77 3.51e-02 GO:0001775 cell activation
1.65 3.63e-02 GO:0042325 regulation of phosphorylation
1.53 3.87e-02 GO:0042127 regulation of cell proliferation
1.75 4.00e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.83 4.17e-02 GO:0008285 negative regulation of cell proliferation
3.46 4.69e-02 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
1.89 4.74e-02 GO:0048598 embryonic morphogenesis
1.63 4.98e-02 GO:0009790 embryo development

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.38 1.94e-04 GO:0044459 plasma membrane part
1.25 2.44e-04 GO:0005886 plasma membrane
2.47 4.37e-04 GO:0031252 cell leading edge
4.71 5.25e-04 GO:0032587 ruffle membrane
1.24 5.59e-04 GO:0071944 cell periphery
4.87 8.78e-04 GO:0042641 actomyosin
3.44 9.82e-04 GO:0005604 basement membrane
1.89 3.08e-03 GO:0031012 extracellular matrix
1.41 3.50e-03 GO:0005856 cytoskeleton
3.52 4.88e-03 GO:0031091 platelet alpha granule
3.35 5.15e-03 GO:0031256 leading edge membrane
2.43 5.51e-03 GO:0005912 adherens junction
4.78 7.40e-03 GO:0001725 stress fiber
1.65 8.48e-03 GO:0030054 cell junction
2.61 1.06e-02 GO:0044420 extracellular matrix part
1.64 1.33e-02 GO:0044431 Golgi apparatus part
2.27 1.35e-02 GO:0070161 anchoring junction
4.46 1.48e-02 GO:0032432 actin filament bundle
2.60 1.63e-02 GO:0030055 cell-substrate junction
1.88 1.74e-02 GO:0005578 proteinaceous extracellular matrix
2.65 1.87e-02 GO:0019898 extrinsic to membrane
2.58 2.89e-02 GO:0005924 cell-substrate adherens junction
3.35 3.25e-02 GO:0031983 vesicle lumen
2.71 3.29e-02 GO:0001726 ruffle
1.87 3.51e-02 GO:0015629 actin cytoskeleton
1.45 4.19e-02 GO:0005794 Golgi apparatus
2.57 4.44e-02 GO:0005925 focal adhesion
3.42 4.84e-02 GO:0031093 platelet alpha granule lumen

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.22 2.83e-08 GO:0005515 protein binding
1.93 2.51e-05 GO:0008092 cytoskeletal protein binding
1.96 5.55e-03 GO:0003779 actin binding
1.51 8.08e-03 GO:0030528 transcription regulator activity
1.08 1.05e-02 GO:0005488 binding
1.49 1.45e-02 GO:0005102 receptor binding
6.25 3.06e-02 GO:0005161 platelet-derived growth factor receptor binding